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Description

Permin® Cream is a topical pesticide medication manufactured by Universal Twin Labs. It is used to treat certain parasitic skin infections caused by microscopic insects. This cream kills not only the existing on the skin insects, but also helps prevent their growth by destroying parasitic eggs. Permin® Cream comprises Permethrin as an active ingredient. Permethrin is a pyrethroid insecticide effective in treating skin infestations caused by mites and other parasites.

Indications:

- pediculosis capitis (infestation with head lice);

- scabies (infestation with Sarcoptes scabiei);

- pubic lice (phthirus pubis).

MOA (mechanism of action):

Permethrin is an anti-lice agent belonging to the pyrethroid chemical class. It disrupts the function of parasites’ neurons interfering with sodium channels. Disruption of neurons causes muscles of an insect to spasm, resulting in its paralysis and death. Permethrin is active against a broad range of pests, including lice, ticks, fleas, mites, and other arthropods. In topical administration, Permethrin is effective against certain ectoparasites, including Pediculus humanus capitis and Sarcoptes scabiei species. Applied to the clothes, it may be effective against certain species of Culicidae (mosquito) family.

Dosage

A single dose of Permin® Cream is curative. You should apply it one time only.

Make sure your skin is clean, dry, and cool prior to applying Permin® Cream. Do not take hot bath or shower before the Permin® Cream application.

Children of 2 months to 2 years old must be treated with Permin® Cream under medical supervision.

How to use Permin® Cream:

1. Wash your hands with soap before the Permin® Cream application.

2. Apply the sufficient amount of Permin® Cream from your neck to the soles of the feet. If you use it for children between 2 months and 2 years of age, Permin® Cream should be applied to their whole body including face, scalp, and ears (excluding areas around the eyes, lips, inside of the nose, and any mucosal surfaces).

3. Gently rub Permin® Cream until absorbed.

4. Make sure that you get the Permin® Cream between your fingers and toes, under the fingernails and toenails, wrists armpits, around genital area and buttocks.

5.Put on clean clothes. Small children should also wear mittens and socks.

6. Do not take shower or bath for 8 hours at least after Permin® Cream application.

7. 8-14 hours after Permin® Cream application, rinse it thoroughly with soap and put on clean cloth.

How much Permin® Cream to use:

Adults and children over 12 years old: about 30 grams of cream.

Children of 5 to 12 years old: about a half of an average adult dose.

Children of 2 months to 5 years old: about 1/8 of an average adult dose.

Remnants of dead scabies or lice and their eggs may cause some itching after the Permin® Cream application. This does not mean the treatment failed and you should reapply it. Re-treatment may be needed in 14 days only if there are still living mites on the skin.

Adults usually do not need to apply Permin® Cream to the face. Do not apply Permin® Cream to your face unless your doctor instructed you to.

Do not use Permin® Cream in patients under 2 months old.

Permin® Cream is for external use only. Do not apply to the mucosal surfaces, eyes, lips, inside of the nose, vagina, penis (urethra) or back passage.

Consult your doctor regarding Permin® Cream use if you are pregnant. Permin® Cream should be used during pregnancy only if clearly needed.

Do not use Permin® Cream during breastfeeding.

Consult your doctor on how to apply Permin® Cream. Use Permin® Cream exactly as directed.

Missing a dose

If you miss a dose you should take it as soon as you remember about your missing. If it is the time for the next dose you should continue your regular dosing schedule. Do not apply a double dose.

Overdose

Do not exceed the doctor's recommended dose. If an overdose occurs and you are feeling unwell, you should seek emergency medical attention or contact your healthcare provider immediately.

Storage

Store at a room temperature from 20 and 25 degrees C (68 and 77 degrees F) away from moisture and heat. Throw away the tube after the expiration date. Keep away from children.

Side effects

The most common side effects associated with the use of Permin® Cream are:

  • allergic reactions (hives, difficult breathing, swelling of your face, lips, tongue, or throat)
  • irritation
  • itching
  • paresthesia (a tingly sensation) at the application site
  • redness
  • burning sensation
  • sore throat
  • abdominal pain
  • nausea and vomiting
  • headache
  • nasal and respiratory irritation

Side effects occurrence does not only depend on the medication you are taking, but also on your overall health and other factors.

Contraindications

Do not apply Permin® Cream if you are allergic to Permethrin or any other pesticide.

Do not apply Permin® Cream if you are allergic to any of the other ingredients comprised in Permin® Cream.

Do not apply Permin® Cream if you have a history of severe allergic reactions associated with using pesticides.

Do not use Permin® Cream in patients under 2 months old.

Do not apply Permin® Cream more than once without doctor’s approval.

Do not take by mouth. Permin® Cream is for use only on the skin. Avoid swallowing or getting in your eyes, lips, inside of the nose, vagina, penis, back passage or on any other mucosal surface. If it does get there, wash with water.

Adults usually do not need to apply Permin® Cream to the face. Do not apply Permin® Cream to your face unless your doctor instructed you to.

Remnants of dead scabies or lice and their eggs may cause some itching after the Permin® Cream application. This does not mean the treatment failed and you should reapply it.

Consult your doctor if you notice living mites on your skin after Permin® Cream application. Re-treatment may be needed if there are still living mites on the skin after 14 days since Permin® Cream application.

Do not take a hot shower or bath before Permin® Cream application.

Do not take shower or bath for 8 hours at least after Permin® Cream application.

Permin® Cream should be rinsed thoroughly within 8-14 hours after application.

Do not apply more Permin® Cream than the amount prescribed for you.

Do not use the Permin® Cream if it has already expired.

Permin® Cream should be used during pregnancy only if clearly needed.

Do not combine breastfeeding and Permin® Cream usage.

Q: How often should I apply Permin® Cream?

A: You need a single application of Permin® Cream (about 30 grams for an adult and from 1/8 to a half of an adult dose for a child depending on the age) leaving it on the skin for 8-14 hours. Do not reapply without doctor’s approval.

Q: Can I use Permin® Cream for my child?

A: You can use Permin® Cream in children over 2 months old.

Q: Can I use Permin® Cream during breastfeeding?

A: It is recommended to discontinue breastfeeding during the Permin® Cream treatment course.

Target Point Shipping Method Tracking Delivery Time Price
Worldwide shipping

Worldwide shipping

Registered Mail  Not trackable 14-21 business days USD 20.00 per order
EMS  Trackable, where available 5-9 business days USD 30.00 per order

Delivery time is:

Registered Mail - 14-21 business days, price - USD 20.00, no signature is required on delivery.
EMS - 5-9 business days, price - USD 30.00, signature is required on delivery.
Your order will be packed safe and secure and dispatched within 24 hours.

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