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Description

Ezanic® Gel is manufactured by Intas. This is a topical treatment for acne and rosacea lesions in a gel formulation. It is also used as an off-label treatment for melasma, non-resectable lentigo maligna, and cutaneous malignant melanoma. This gel has strong antibacterial, anti-inflammatory, and exfoliating properties. Ezanic® Gel comprises Azelaic Acid as a key ingredient. This is an organic compound of the dicarboxylic acids class. Azelaic Acid helps reduce pigmentation, so it is useful for darker skinned patients whose acne spots leave persistent brown marks (post-inflammatory pigmentation) or who have melasma.

Rosacea is a long-term skin disease characterized by flushing, redness, bumps, swelling, and visible blood vessels. This skin condition occurs when the immune system responds to the overgrowth of Antimicrobial peptides (AMPs), also called host defense peptides (HDPs), in the skin. Overproduction of AMPs can be caused by blood vessel abnormalities, microscopic mites, and Helicobacter pylori bacteria among other reasons.

Acne (acne vulgaris) is also a long-term inflammatory skin disorder characterized by clogged pores, pimples, whiteheads, cysts, non-inflamed comedones, and possible scarring on the face, neck, chest, and back. It occurs as an immune response to P. acnes bacteria (Propionibacterium acnes) overgrowth. P. acnes overabundance is associated with genetic predisposition or increase in androgen hormones.

MOA (mechanism of action):

Azelaic Acid acts as an antibacterial agent by suppressing the synthesis of cellular protein and several oxidoreductive enzymes in bacteria, therefore inhibits bacterial growth and reduces the quantity of AMPs in the body. As an exfoliant, Azelaic Acid normalizes keratin forming process, which helps reduce the thickness of the stratum corneum (the outermost layer of the skin) leaving the skin smooth and free from dead cells residue.

Dosage

Ezanic® Gel is for external use only. Do not apply to your eyes, mouth, inside of the nose, private parts, and any other mucosal surface.

Ezanic® Cream is for external use only. Do not apply to your eyes, mouth, inside of the nose, private parts, and any other mucosal surface.

For acne: Apply Ezanic® Cream twice daily, in the morning and at bedtime. This cream should be applied for 1 month at least. Consult your doctor regarding the further use of Ezanic® Cream.

In case your acne has not improved after 1 month of treatment, discontinue the Ezanic® Cream use and seek medical advice.

For rosacea: Apply Ezanic® Cream twice daily, in the morning and at bedtime. This cream should be applied for 2 months at least. Consult your doctor regarding the further use of Ezanic® Cream.

In case your rosacea has not improved after 2 months of treatment, discontinue the Ezanic® Cream use and seek medical advice.

How to use Ezanic® Gel:

1. Wash your hands and the affected area with mild soap or cleanser, pat dry.

2. Apply a thin layer of the gel to the affected areas.

3. Rub gently until absorbed.

4. Wash your hands after the gel application.

Precautions

If skin sensitization or irritation occurs, reduce the number of Ezanic® Gel daily applications to one time, preferably in the evening. After a week of such application schedule, start using Ezanic® Gel 2 times a day. If necessary, interrupt the treatment course for a few days during the irritation event.

Do not cover the gel application site with bandage or other covering.

Do not use Ezanic® Gel for longer than 12 months.

Do not use Ezanic® Gel more than 2 times a day.

Missing a dose

If you miss a dose you should take it as soon as you remember about your missing. If it is the time for the next dose you should continue your regular dosing schedule. Do not apply a double dose.

Overdose

Do not exceed the doctor's recommended dose. If an overdose occurs and you are feeling unwell, you should seek emergency medical attention or contact your healthcare provider immediately.

Storage

Store at a room temperature from 20 and 25 degrees C (68 and 77 degrees F) away from moisture and heat. Throw away the tube after the expiration date. Keep away from children.

Side effects

The most common side effects associated with the use of Ezanic® Gel are:

  • burning or tingling
  • itching
  • abnormal redness of the skin (erythema)
  • scaling
  • dry skin
  • skin discoloration
  • irritation at the application site
  • oily skin
  • loss of skin color
  • discomfort or swelling

Side effects occurrence does not only depend on the medication you are using, but also on your overall health and other factors.

Contraindications

Do not apply Ezanic® Gel if you are allergic to Azelaic Acid.

Do not apply Ezanic® Gel if you are allergic to any of the other ingredients comprised in Ezanic® Gel.

Do not use Ezanic® Gel if you have asthma or herpes.

Do not use Ezanic® Gel if you are pregnant or breastfeeding without your doctor’s approval.

Do not use Ezanic® Gel in patients under the age of 12.

Do not take by mouth. Ezanic® Gel is for use only on the skin.

Q: Is Ezanic® Gel is safe to use in children?

A: Ezanic® Gel is completely safe for patient over 12 years old.

Q: Can I use Ezanic® Gel during breastfeeding?

A: Although Ezanic® Gel is considered as mostly safe for lactating women, you should not start the treatment course without your doctor’s approval.

Q: Is Ezanic® Gel effective in treating acne?

A: Yes. Ezanic® Gel kills acne-causing bacteria and reduces the amount of breakouts and clogged pores.

Target Point Shipping Method Tracking Delivery Time Price
Worldwide shipping

Worldwide shipping

Registered Mail  Not trackable 14-21 business days USD 20.00 per order
EMS  Trackable, where available 5-9 business days USD 30.00 per order

Delivery time is:

Registered Mail - 14-21 business days, price - USD 20.00, no signature is required on delivery.
EMS - 5-9 business days, price - USD 30.00, signature is required on delivery.
Your order will be packed safe and secure and dispatched within 24 hours.

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